Recommendations for obesity prevention and treatment confront biological adaptations

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Recommendations for obesity prevention and treatment confront biological adaptations Share This Page
  February 12, 2015Experts suggest obesity is a chronic disease with largely biological causes. "For most individuals, these biological adaptations need to be addressed for weight loss to be sustained long-term," they note.

Experts suggest obesity is a chronic disease with largely biological causes. "For most individuals, these biological adaptations need to be addressed for weight loss to be sustained long-term," they note. "We believe these mechanisms largely explain the poor long-term success rates of lifestyle modification, and obligate clinicians to go beyond mere recommendations to eat less and move more." They suggest that many clinicians may not be familiar enough with the reasons that people with obesity face in achieving and maintaining weight loss. The authors' clinical recommendations for obesity prevention and treatment include proactively addressing prevention with overweight patients, focusing on lifestyle choices, and continuing to monitor progress and adjust strategy as necessary. In terms of treatment, they recommend encouraging patients with obesity to consider treatment, even if it is not the primary complaint; considering biologically based interventions; implementing a multifaceted treatment strategy; recommending surgery when appropriate; and informing patients of the challenges to weight-loss maintenance.

The Lancet Diabetes & Endocrinology (02/11/2015) Ochner, Christopher N.; Tsai, Adam G.; Kushner, Robert F.; et al.

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